Abstract
A family of proteins has been identified whose members, the Shanks, physically link two major receptor complexes at excitatory synapses - NMDA receptors and metabotropic glutamate receptors.
MeSH terms
-
Adaptor Proteins, Signal Transducing*
-
Animals
-
Carrier Proteins / chemistry
-
Carrier Proteins / genetics
-
Carrier Proteins / physiology*
-
Cortactin
-
Homer Scaffolding Proteins
-
Humans
-
Macromolecular Substances
-
Microfilament Proteins / chemistry
-
Microfilament Proteins / physiology
-
Models, Molecular
-
Models, Neurological
-
Nerve Tissue Proteins / chemistry
-
Nerve Tissue Proteins / genetics
-
Nerve Tissue Proteins / physiology*
-
Neuropeptides / chemistry
-
Neuropeptides / physiology
-
Protein Structure, Tertiary
-
Receptors, Metabotropic Glutamate / chemistry*
-
Receptors, Metabotropic Glutamate / physiology
-
Receptors, N-Methyl-D-Aspartate / chemistry*
-
Receptors, N-Methyl-D-Aspartate / physiology
-
SAP90-PSD95 Associated Proteins
-
Signal Transduction
-
Synapses / chemistry*
-
Synapses / ultrastructure
-
Two-Hybrid System Techniques
Substances
-
Adaptor Proteins, Signal Transducing
-
Carrier Proteins
-
Cortactin
-
Homer Scaffolding Proteins
-
Macromolecular Substances
-
Microfilament Proteins
-
Nerve Tissue Proteins
-
Neuropeptides
-
Receptors, Metabotropic Glutamate
-
Receptors, N-Methyl-D-Aspartate
-
SAP90-PSD95 Associated Proteins
-
SHANK2 protein, human
-
SHANK3 protein, human
-
Shank1 protein, rat
-
Shank2 protein, rat
-
postsynaptic density proteins