Transcranial magnetic stimulation in cognitive neuroscience--virtual lesion, chronometry, and functional connectivity

Curr Opin Neurobiol. 2000 Apr;10(2):232-7. doi: 10.1016/s0959-4388(00)00081-7.

Abstract

Fifteen years after its introduction by Anthony Barker, transcranial magnetic stimulation (TMS) appears to be 'coming of age' in cognitive neuroscience and promises to reshape the way we investigate brain-behavior relations. Among the many methods now available for imaging the activity of the human brain, magnetic stimulation is the only technique that allows us to interfere actively with brain function. As illustrated by several experiments over the past couple of years, this property of TMS allows us to investigate the relationship between focal cortical activity and behavior, to trace the timing at which activity in a particular cortical region contributes to a given task, and to map the functional connectivity between brain regions.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Behavior / physiology
  • Brain / physiology*
  • Brain Diseases / complications
  • Brain Diseases / therapy
  • Chronobiology Phenomena / physiology*
  • Cognition / physiology*
  • Electric Stimulation / instrumentation
  • Electric Stimulation / methods*
  • Electromagnetic Fields
  • Functional Laterality / physiology
  • Humans
  • Mental Disorders / etiology
  • Mental Disorders / therapy
  • Neurosciences / instrumentation*
  • Physical Stimulation / adverse effects
  • Physical Stimulation / instrumentation
  • Reaction Time / physiology
  • Transcranial Magnetic Stimulation / instrumentation*