The idea that sensory information is represented by the temporal firing patterns of neurons or entire networks, rather than by firing rates measured over long integration times, has recently gained increasing experimental support. A number of mechanisms that help to preserve temporal information in ascending sensory systems have been identified, and the role of inhibition in these processes has been characterized. Furthermore, it has become obvious that temporal processing and the representation of sensory events by temporal spike patterns are highly dependent upon the behavioral state of the animal or experimental subject.