Bistability in pulse propagation in networks of excitatory and inhibitory populations

Phys Rev Lett. 2001 Apr 30;86(18):4179-82. doi: 10.1103/PhysRevLett.86.4179.

Abstract

We study the propagation of traveling solitary pulses in one-dimensional networks of excitatory and inhibitory integrate-and-fire neurons. Slow pulses, during which inhibitory cells fire well before neighboring excitatory cells, can propagate along the network at intermediate inhibition levels. At higher levels, they destabilize via a Hopf bifurcation. There is a bistable parameter regime in which both fast and slow pulses can propagate. Lurching pulses with spatiotemporal periodicity can propagate in regimes for which continuous pulses do not exist.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Membrane Potentials / physiology
  • Models, Neurological*
  • Nerve Net / physiology*
  • Neural Conduction / physiology*
  • Neurons / physiology*