Working memory and the suppression of reflexive saccades

J Cogn Neurosci. 2002 Jan 1;14(1):95-103. doi: 10.1162/089892902317205357.

Abstract

Conscious behavioral intentions can frequently fail under conditions of attentional depletion. In attempting to trace the cognitive origin of this effect, we hypothesized that failures of action control--specifically, oculomotor movement--can result from the imposition of fronto-executive load. To evaluate this prediction, participants performed an antisaccade task while simultaneously completing a working-memory task that is known to make variable demands on prefrontal processes (n-back task, see Jonides et al., 1997). The results of two experiments are reported. As expected, antisaccade error rates were increased in accordance with the fronto-executive demands of the n-back task (Experiment 1). In addition, the debilitating effects of working-memory load were restricted to the inhibitory component of the antisaccade task (Experiment 2). These findings corroborate the view that working memory operations play a critical role in the suppression of prepotent behavioral responses.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Attention / physiology
  • Frontal Lobe / physiology
  • Humans
  • Memory, Short-Term / physiology*
  • Psychomotor Performance / physiology
  • Reflex / physiology*
  • Saccades / physiology*
  • Volition / physiology