Abstract
Immunocytochemical and ultrastructural evidence is presented indicating that direct inputs from the hippocampal CA1 field to prelimbic (area 32) and infralimbic (area 25) cortices in the rat, innervate not only 'spiny' (presumed pyramidal) neurons but also monosynaptically contact NADPH-diaphorase reactive cells and parvalbumin-containing local circuit neurons-the latter cell type is shown to be GABA immunoreactive. Similar evidence of direct CA1 input to local circuit neurons containing either calbindin or calretinin was not found.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Afferent Pathways / cytology
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Afferent Pathways / metabolism
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Afferent Pathways / physiology
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Animals
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Calbindin 2
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Calbindins
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Electrophysiology
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Hippocampus / cytology
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Hippocampus / physiology*
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Hippocampus / ultrastructure
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Immunohistochemistry
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Limbic System / metabolism
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Limbic System / physiology
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Male
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NADPH Dehydrogenase / metabolism*
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Neurons, Afferent / physiology*
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Neurons, Afferent / ultrastructure
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Parvalbumins / physiology*
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Prefrontal Cortex / cytology
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Prefrontal Cortex / metabolism
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Prefrontal Cortex / physiology*
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Rats
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Rats, Sprague-Dawley
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S100 Calcium Binding Protein G / metabolism
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Synapses / physiology*
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gamma-Aminobutyric Acid / metabolism
Substances
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Calb2 protein, rat
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Calbindin 2
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Calbindins
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Parvalbumins
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S100 Calcium Binding Protein G
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gamma-Aminobutyric Acid
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NADPH Dehydrogenase