Abstract
Prolonged exposure of the neonatal kitten to a lipopolysaccharide results in a telencephalic leucoencephalopathy characterized by astrogliosis and necrosis. The visceral organs of neonatal kittens and the telencephalon of mature cats are relatively resistent to the adverse effects of this lipopolysaccharide.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Age Factors
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Animals
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Animals, Newborn*
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Cats
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Cysts / chemically induced
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Disease Models, Animal*
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Dose-Response Relationship, Drug
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Endotoxins / administration & dosage
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Endotoxins / toxicity*
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Gliosis / chemically induced
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Leukoencephalopathy, Progressive Multifocal / chemically induced*
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Leukoencephalopathy, Progressive Multifocal / pathology
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Lipopolysaccharides / toxicity
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Necrosis / chemically induced
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Telencephalon*
Substances
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Endotoxins
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Lipopolysaccharides