Abstract
Drosophila geneticists have uncovered roles for microRNAs in the coordination of cell proliferation and cell death during development, and in stress resistance and fat metabolism. In C. elegans, a homolog of the well-known fly developmental regulator hunchback acts downstream of the microRNAs lin-4 and let-7 in a pathway controlling developmental timing.
MeSH terms
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Animals
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Apoptosis / genetics
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Caenorhabditis elegans / genetics*
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Caenorhabditis elegans / growth & development
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Cell Division / genetics
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Drosophila melanogaster / genetics*
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Drosophila melanogaster / growth & development
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Gene Expression Regulation, Developmental / genetics
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MicroRNAs / genetics*
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Protein Biosynthesis / genetics
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RNA, Messenger / genetics*