Abstract
Carbohydrate-carrying molecules in the nervous system have important roles during development, regeneration and synaptic plasticity. Carbohydrates mediate interactions between recognition molecules, thereby contributing to the formation of a complex molecular meshwork at the cell surface and in the extracellular matrix. The tremendous structural diversity of glycan chains allows for immense combinatorial possibilities that might underlie the fine-tuning of cell-cell and cell-matrix interactions.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amino Acid Sequence
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Animals
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Carbohydrate Conformation
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Carbohydrate Sequence
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Cell Communication*
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Circadian Rhythm / physiology
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Extracellular Matrix / metabolism*
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Humans
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Molecular Sequence Data
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Nervous System Diseases / metabolism
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Neural Cell Adhesion Molecules / genetics
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Neural Cell Adhesion Molecules / metabolism
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Neuronal Plasticity
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Neurons / chemistry
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Neurons / physiology*
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Polysaccharides / chemistry
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Polysaccharides / metabolism*
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Sequence Alignment
Substances
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Neural Cell Adhesion Molecules
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Polysaccharides