[Enzymes of purine nucleotide metabolism in assessment of the functional competence of the immune system]

Biomed Khim. 2005 Mar-Apr;51(2):199-205.
[Article in Russian]

Abstract

Blood lymphocyte activities of 5'-nucleotidases, adenosine deaminase and AMP deaminase have been investigated for evaluation of immune system state of albino rats under normal conditions, immobilization stress and effect of radiation. Stress-induced reactions were characterized by changes of activities of these enzymes. However the ratios of activities 5'- nucleotidase/AMP-deaminase (coefficient A) and adenosine-deaminase/AMP-deaminase (coefficient B) were even more informative than separate analysis of these enzymes.

Publication types

  • English Abstract

MeSH terms

  • 5'-Nucleotidase / metabolism*
  • AMP Deaminase / metabolism*
  • Adenosine Deaminase / metabolism*
  • Animals
  • Antibody Formation
  • Gamma Rays
  • Immobilization
  • Immunity, Cellular
  • Lymphocytes / enzymology*
  • Purine Nucleotides / metabolism
  • Radiation Injuries, Experimental / immunology*
  • Rats
  • Stress, Psychological / etiology
  • Stress, Psychological / immunology*

Substances

  • Purine Nucleotides
  • 5'-Nucleotidase
  • Adenosine Deaminase
  • AMP Deaminase