Abstract
We report the use of chemically-functionalized water soluble single-walled carbon nanotube (SWNT) graft copolymers for modulation of outgrowth of neuronal processes. The graft copolymers were prepared by the functionalization of SWNTs with poly-m-aminobenzene sulphonic acid and polyethylene glycol. When added to the culturing medium, these functionalized water soluble SWNTs were able to increase the length of various neuronal processes.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Biocompatible Materials / chemistry*
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Cell Culture Techniques / methods*
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Cell Enlargement
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Cells, Cultured
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Crystallization / methods
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Culture Media / chemistry
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Hippocampus / cytology
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Hippocampus / physiology
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Materials Testing
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Nanotechnology / methods*
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Nanotubes, Carbon / analysis
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Nanotubes, Carbon / chemistry*
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Nanotubes, Carbon / ultrastructure
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Neurites / physiology*
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Neurites / ultrastructure
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Neurons / cytology*
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Neurons / physiology*
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Particle Size
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Rats
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Rats, Sprague-Dawley
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Solubility
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Surface Properties
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Water / chemistry
Substances
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Biocompatible Materials
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Culture Media
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Nanotubes, Carbon
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Water