fruitless regulates aggression and dominance in Drosophila

Nat Neurosci. 2006 Dec;9(12):1469-71. doi: 10.1038/nn1809. Epub 2006 Nov 19.

Abstract

When competing for resources, two Drosophila melanogaster flies of the same sex fight each other. Males and females fight with distinctly different styles, and males but not females establish dominance relationships. Here we show that sex-specific splicing of the fruitless gene plays a critical role in determining who and how a fly fights, and whether a dominance relationship forms.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aggression / physiology*
  • Alternative Splicing / genetics
  • Alternative Splicing / physiology
  • Animals
  • Behavior, Animal / physiology*
  • Dominance-Subordination*
  • Drosophila / genetics*
  • Drosophila Proteins / genetics*
  • Drosophila Proteins / physiology
  • Female
  • Male
  • Nerve Tissue Proteins / genetics*
  • Nerve Tissue Proteins / physiology
  • Sex Characteristics
  • Transcription Factors / genetics*
  • Transcription Factors / physiology

Substances

  • Drosophila Proteins
  • Nerve Tissue Proteins
  • Transcription Factors
  • fru protein, Drosophila