Caenorhabditis elegans: a model system for systems neuroscience

Curr Opin Neurobiol. 2009 Dec;19(6):637-43. doi: 10.1016/j.conb.2009.09.009. Epub 2009 Nov 4.

Abstract

The nematode Caenorhabditis elegans is an excellent model organism for a systems-level understanding of neural circuits and behavior. Advances in the quantitative analyses of behavior and neuronal activity, and the development of new technologies to precisely control and monitor the workings of interconnected circuits, now allow investigations into the molecular, cellular, and systems-level strategies that transform sensory inputs into precise behavioral outcomes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Behavior, Animal / physiology*
  • Caenorhabditis elegans / physiology*
  • Humans
  • Models, Neurological*
  • Neurosciences*