State dependence of olfactory perception as a function of taste cortical inactivation

Nat Neurosci. 2010 Feb;13(2):158-9. doi: 10.1038/nn.2463. Epub 2009 Dec 20.

Abstract

As anyone who has suffered through a head cold knows, food eaten when the olfactory system is impaired tastes 'wrong', an experience that leads many to conclude that taste stimuli are processed normally only when the olfactory system is unimpaired. Evidence that the taste system influences olfactory perception, however, has been vanishingly rare. We found just such an influence; if taste cortex was inactivated when an odor was first presented, later presentations were properly appreciated only if taste cortex was again inactivated.

MeSH terms

  • Animals
  • Cerebral Cortex / drug effects
  • Cerebral Cortex / physiology*
  • Detergents
  • Feeding Behavior / drug effects
  • Feeding Behavior / physiology
  • Female
  • Food Preferences / drug effects
  • Food Preferences / physiology
  • GABA Agonists / pharmacology
  • Learning / drug effects
  • Learning / physiology
  • Memory / drug effects
  • Memory / physiology
  • Muscimol / pharmacology
  • Odorants
  • Olfaction Disorders / chemically induced
  • Olfactory Perception / drug effects
  • Olfactory Perception / physiology*
  • Physical Stimulation
  • Rats
  • Rats, Long-Evans
  • Social Behavior
  • Taste Perception / drug effects
  • Taste Perception / physiology*
  • Time Factors

Substances

  • Detergents
  • GABA Agonists
  • Muscimol