Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor

Nature. 1979 Mar 29;278(5703):423-7. doi: 10.1038/278423a0.

Abstract

The nucleotide sequence of a 1,091-base pair cloned cDNA insert encoding bovine corticotropin-beta-lipotropin precursor mRNA is reported. The corresponding amino acid sequence indicates that the precursor protein consists of repetitive units and includes a third melanotropin sequence in its cryptic portion. Pairs of lysine and arginine residues separate the component peptides of the precursor.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adrenocorticotropic Hormone / genetics*
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cattle
  • Codon
  • DNA, Recombinant
  • Endorphins / genetics
  • Genes
  • Melanocyte-Stimulating Hormones / genetics
  • Protein Precursors / genetics*
  • RNA, Messenger / genetics
  • beta-Lipotropin / genetics*

Substances

  • Codon
  • DNA, Recombinant
  • Endorphins
  • Protein Precursors
  • RNA, Messenger
  • Adrenocorticotropic Hormone
  • Melanocyte-Stimulating Hormones
  • beta-Lipotropin

Associated data

  • GENBANK/J00016
  • GENBANK/J00017
  • GENBANK/J00019
  • GENBANK/J00021