Seeing Anew through Interneuron Transplantation

Jared N Levine; Yu Gu; Jianhua Cang

doi:10.1016/j.neuron.2015.05.003

Seeing Anew through Interneuron Transplantation

Neuron. 2015 May 20;86(4):858-860. doi: 10.1016/j.neuron.2015.05.003.

Authors

Jared N Levine¹, Yu Gu², Jianhua Cang³

Affiliations

¹ Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA; Interdepartmental Neuroscience Program, Northwestern University, Evanston, IL 60208, USA.
² Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
³ Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA. Electronic address: cang@northwestern.edu.

PMID: 25996130
DOI: 10.1016/j.neuron.2015.05.003

Abstract

Critical periods are developmental time windows during which neuronal connections are shaped by experience. In this issue of Neuron, Davis et al. (2015) show that transplantation of embryonic inhibitory interneurons can reactivate critical period plasticity and reverse amblyopia in the visual cortex of adult mice.

Publication types

Comment

MeSH terms

Animals
Critical Period, Psychological*
Neural Inhibition / physiology*
Neuronal Plasticity / physiology*
Neurons / physiology*
Vision, Ocular / physiology*
Visual Cortex / growth & development*

Grants and funding

R01 EY020950/EY/NEI NIH HHS/United States