Inhibition of the lysosomal pathway of protein degradation in isolated rat hepatocytes by ammonia, methylamine, chloroquine and leupeptin

Eur J Biochem. 1979 Apr 2;95(2):215-25. doi: 10.1111/j.1432-1033.1979.tb12956.x.
No abstract available

MeSH terms

  • Ammonia / pharmacology*
  • Animals
  • Chloroquine / pharmacology*
  • Depression, Chemical
  • In Vitro Techniques
  • Leupeptins / pharmacology*
  • Liver / drug effects
  • Liver / metabolism*
  • Lysosomes / drug effects
  • Lysosomes / metabolism*
  • Male
  • Methylamines / pharmacology*
  • Oligopeptides / pharmacology*
  • Oxygen / pharmacology
  • Proteins / metabolism*
  • Rats
  • Time Factors
  • Valine / metabolism

Substances

  • Leupeptins
  • Methylamines
  • Oligopeptides
  • Proteins
  • Ammonia
  • Chloroquine
  • Valine
  • Oxygen