Vesicle fusion from yeast to man

Nature. 1994 Jul 21;370(6486):191-3. doi: 10.1038/370191a0.

Abstract

Membrane budding and fusion occur in all eukaryotic cells. Their underlying mechanisms have been studied in mammalian neurons and in yeast, a simple eukaryote. The differences between these two systems would suggest that fusion events in yeast and the neuron would operate by different mechanisms, but recent advances indicate that this is not true.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Carrier Proteins / metabolism
  • Exocytosis
  • GTP-Binding Proteins / metabolism
  • Humans
  • Membrane Fusion* / genetics
  • Membrane Proteins / metabolism
  • Nerve Tissue Proteins / metabolism
  • Neurons / metabolism
  • R-SNARE Proteins
  • Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins
  • Synaptic Membranes / metabolism
  • Vesicular Transport Proteins*
  • Yeasts

Substances

  • Carrier Proteins
  • Membrane Proteins
  • Nerve Tissue Proteins
  • R-SNARE Proteins
  • Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins
  • Vesicular Transport Proteins
  • GTP-Binding Proteins