Abstract
The distribution of neural visinin-like Ca(2+)-binding protein 2 (NVP2) in adult rat brain was analyzed by immunoblot and immunohistochemical methods. NVP2 immunoreactivity was expressed intensely in the pyramidal cells of the CA1 and 2 regions of Ammon's horn, the granule cells of the dentate gyrus and the pyramidal cells of the cerebral cortex layers II to VI, moderately in the pyramidal-shaped cells of the anterior olfactory nucleus and large spindle-shaped cells of the globus pallidus, and weakly in neurons in the nucleus accumbens and the anterior and dorsomedial thalamus. In most cell types, NVP2 immunoreactivity was located in the cytoplasm and plasma membrane of the cell bodies and dendrites.
MeSH terms
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Animals
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Brain / cytology
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Brain Chemistry / physiology*
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Calcium-Binding Proteins / immunology
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Calcium-Binding Proteins / metabolism*
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Carrier Proteins / immunology
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Carrier Proteins / metabolism
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Dendrites / metabolism
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Dendrites / ultrastructure
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Immunoblotting
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Immunohistochemistry
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Maltose-Binding Proteins
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Nerve Tissue Proteins / immunology
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Nerve Tissue Proteins / metabolism*
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Neurocalcin
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Neurons / metabolism
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Neurons / ultrastructure
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Polymerase Chain Reaction
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Pyramidal Cells / drug effects
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Pyramidal Cells / metabolism
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Pyramidal Cells / ultrastructure
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Rats
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Rats, Sprague-Dawley
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Receptors, Calcium-Sensing*
Substances
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Calcium-Binding Proteins
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Carrier Proteins
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Maltose-Binding Proteins
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NVP2 protein, rat
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Nerve Tissue Proteins
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Neurocalcin
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Receptors, Calcium-Sensing
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Vsnl1 protein, rat
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visinin