Abstract
The POU proteins BRN-3a, -3b and -3c are transcription factors encoded by separate genes that are differentially expressed during neural development. Comparison of genomic and cDNA sequences revealed similar exon/intron structures for Brn-3a and -3c genes, whereas the Brn-3b gene appeared to contain an intronless coding region. Fluorescence in situ hybridization experiments with mouse chromosomes showed that Brn-3a maps to mouse chromosome 14E1-3, Brn-3b to XF1-5 and Brn-3c to 18B3-E1.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Aging / genetics
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Amino Acid Sequence
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Animals
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Animals, Newborn
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Base Sequence
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Chromosome Mapping*
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DNA-Binding Proteins / genetics*
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Embryo, Mammalian
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Exons
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Fibroblasts / cytology
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In Situ Hybridization, Fluorescence
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Introns
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Lymphoma
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Mice / genetics*
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Mice / growth & development
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Mice, Inbred Strains
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Molecular Sequence Data
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Polymerase Chain Reaction
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Transcription Factor Brn-3
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Transcription Factor Brn-3A
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Transcription Factor Brn-3B
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Transcription Factor Brn-3C
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Transcription Factors / genetics*
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Tumor Cells, Cultured
Substances
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DNA-Binding Proteins
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Pou4f1 protein, mouse
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Transcription Factor Brn-3
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Transcription Factor Brn-3A
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Transcription Factor Brn-3B
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Transcription Factor Brn-3C
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Transcription Factors
Associated data
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GENBANK/S69350
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GENBANK/S69351
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GENBANK/S69352