Nonword repetition as a behavioural marker for inherited language impairment: evidence from a twin study

J Child Psychol Psychiatry. 1996 May;37(4):391-403. doi: 10.1111/j.1469-7610.1996.tb01420.x.

Abstract

The Children's Nonword Repetition Test (CNRep) was given 39 children with persistent language impairment (LI), 13 with a history of having received speech-language therapy (resolved LI), and 79 controls, all aged from 7 to 9 years. The children with LI were twins who had participated in a previous genetic study. Children with resolved LI, as well as those with persistent LI, were significantly impaired on the CNRep. Comparisons of MZ and DZ twins indicated significant heritability of a CNRep deficit. It is concluded that CNRep provides a marker of the phenotype of heritable forms of developmental language impairment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Twin Study

MeSH terms

  • Child
  • Diseases in Twins / genetics*
  • Female
  • Genetic Markers / genetics*
  • Humans
  • Language Development Disorders / diagnosis
  • Language Development Disorders / genetics*
  • Language Development Disorders / therapy
  • Language Tests*
  • Language Therapy
  • Male
  • Phenotype
  • Phonetics
  • Speech Disorders / diagnosis
  • Speech Disorders / genetics
  • Speech Disorders / therapy
  • Speech Therapy
  • Twins, Dizygotic / genetics
  • Twins, Monozygotic / genetics

Substances

  • Genetic Markers