Rho family GTP-binding proteins in growth cone signalling

L Luo; L Y Jan; Y N Jan

doi:10.1016/s0959-4388(97)80124-9

Rho family GTP-binding proteins in growth cone signalling

Curr Opin Neurobiol. 1997 Feb;7(1):81-6. doi: 10.1016/s0959-4388(97)80124-9.

Authors

L Luo¹, L Y Jan, Y N Jan

Affiliation

¹ Howard Hughes Medical Institute, Department of Physiology, University of California at San Francisco, California 94143, USA. lluo@standford.edu

PMID: 9039798
DOI: 10.1016/s0959-4388(97)80124-9

Abstract

Rho family GTP-binding proteins regulate various aspects of the actin cytoskeleton in a wide variety of organisms. Recent evidence suggests that they may also be important components of the signalling pathways that link the reception of extracellular cues to the regulation of the cytoskeleton in neuronal growth cones.

Publication types

Review

MeSH terms

Actins / physiology
Animals
Cell Cycle Proteins / physiology*
Cytoskeleton / physiology
GTP-Binding Proteins / physiology*
Humans
Infant
Neurons / physiology*
Signal Transduction*
cdc42 GTP-Binding Protein, Saccharomyces cerevisiae
rac GTP-Binding Proteins
rhoA GTP-Binding Protein

Substances

Actins
Cell Cycle Proteins
GTP-Binding Proteins
cdc42 GTP-Binding Protein, Saccharomyces cerevisiae
rac GTP-Binding Proteins
rhoA GTP-Binding Protein