Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases?

Neuron. 1997 Dec;19(6):1147-50. doi: 10.1016/s0896-6273(00)80405-5.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / metabolism
  • Brain / pathology*
  • Humans
  • Huntingtin Protein
  • Huntington Disease / genetics
  • Huntington Disease / pathology
  • Mice
  • Mice, Transgenic
  • Nerve Tissue Proteins / biosynthesis
  • Nerve Tissue Proteins / genetics
  • Neurodegenerative Diseases / genetics*
  • Neurodegenerative Diseases / pathology*
  • Neurons / metabolism
  • Neurons / pathology*
  • Neurons / ultrastructure
  • Nuclear Proteins / biosynthesis
  • Nuclear Proteins / genetics
  • Peptides*
  • Purkinje Cells / pathology

Substances

  • HTT protein, human
  • Htt protein, mouse
  • Huntingtin Protein
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • Peptides
  • polyglutamine