GABAB receptors: drugs meet clones

Curr Opin Neurobiol. 1998 Jun;8(3):345-50. doi: 10.1016/s0959-4388(98)80059-7.

Abstract

Recently, the long-awaited cloning of the GABAB receptors, the last of the major known neurotransmitter receptors to be identified, has been reported. In addition to an emerging molecular understanding, there have been advances in discerning the specific coupling partners of GABAB receptors in the brain.

Publication types

  • Review

MeSH terms

  • Baclofen / therapeutic use*
  • Brain Chemistry / physiology
  • Cloning, Molecular
  • GABA Agonists / therapeutic use*
  • GABA-B Receptor Agonists
  • Humans
  • Receptors, GABA-B / chemistry
  • Receptors, GABA-B / genetics*
  • Signal Transduction / physiology*
  • gamma-Aminobutyric Acid / physiology*

Substances

  • GABA Agonists
  • GABA-B Receptor Agonists
  • Receptors, GABA-B
  • gamma-Aminobutyric Acid
  • Baclofen