Mitochondrial oversight of cellular Ca2+ signaling

Curr Opin Neurobiol. 1998 Jun;8(3):398-404. doi: 10.1016/s0959-4388(98)80067-6.

Abstract

Mitochondria, the metabolic powerhouses of the cell, can sequester and release large amounts of Ca2+. This import and export of Ca2+ helps to adjust energy production to cellular needs. Recent advances show that mitochondrial Ca2+ fluxes play a major role in normal Ca2+ signaling.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Calcium / physiology*
  • Calcium Channels / physiology*
  • Membrane Potentials / physiology
  • Mitochondria / chemistry
  • Mitochondria / physiology*
  • Signal Transduction / physiology*

Substances

  • Calcium Channels
  • Calcium