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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1973 2
1990 1
1991 1
1992 3
1993 3
1994 3
1995 5
1996 3
1998 3
1999 2
2001 1
2003 1
2004 1
2006 2
2007 1
2008 3
2009 2
2010 1
2011 4
2012 2
2013 4
2014 1
2017 1
2018 1
2021 1
2023 2
2024 0

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52 results

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Page 1
Mixture-based synthetic combinatorial libraries.
Houghten RA, Pinilla C, Appel JR, Blondelle SE, Dooley CT, Eichler J, Nefzi A, Ostresh JM. Houghten RA, et al. Among authors: appel jr. J Med Chem. 1999 Sep 23;42(19):3743-78. doi: 10.1021/jm990174v. J Med Chem. 1999. PMID: 10508425 Review. No abstract available.
Synthetic small-molecule prohormone convertase 2 inhibitors.
Kowalska D, Liu J, Appel JR, Ozawa A, Nefzi A, Mackin RB, Houghten RA, Lindberg I. Kowalska D, et al. Among authors: appel jr. Mol Pharmacol. 2009 Mar;75(3):617-25. doi: 10.1124/mol.108.051334. Epub 2008 Dec 12. Mol Pharmacol. 2009. PMID: 19074544 Free PMC article.
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign.
Doering SR, Freeman K, Debevec G, Geer P, Santos RG, Lavoi TM, Giulianotti MA, Pinilla C, Appel JR, Houghten RA, Ericson MD, Haskell-Luevano C. Doering SR, et al. Among authors: appel jr. J Med Chem. 2021 May 13;64(9):5577-5592. doi: 10.1021/acs.jmedchem.0c02041. Epub 2021 Apr 22. J Med Chem. 2021. PMID: 33886285 Free PMC article.
Integrating computational and mixture-based screening of combinatorial libraries.
Yongye AB, Pinilla C, Medina-Franco JL, Giulianotti MA, Dooley CT, Appel JR, Nefzi A, Scior T, Houghten RA, Martínez-Mayorga K. Yongye AB, et al. Among authors: appel jr. J Mol Model. 2011 Jun;17(6):1473-82. doi: 10.1007/s00894-010-0850-1. Epub 2010 Sep 21. J Mol Model. 2011. PMID: 20853183
Correction to "Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput 'Unbiased' Screening Campaign".
Doering SR, Freeman K, Debevec G, Geer P, Santos RG, Lavoi TM, Giulianotti MA, Pinilla C, Appel JR, Houghten RA, Ericson MD, Haskell-Luevano C. Doering SR, et al. Among authors: appel jr. J Med Chem. 2023 May 25;66(10):7063-7065. doi: 10.1021/acs.jmedchem.3c00588. Epub 2023 May 8. J Med Chem. 2023. PMID: 37155917 No abstract available.
52 results