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Page 1
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport.
J Neurosci. 2003 Jun 1;23(11):4499-508. doi: 10.1523/JNEUROSCI.23-11-04499.2003.
J Neurosci. 2003.
PMID: 12805290
Free PMC article.
ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons.
Helguera P, Pelsman A, Pigino G, Wolvetang E, Head E, Busciglio J.
Helguera P, et al. Among authors: pelsman a.
J Neurosci. 2005 Mar 2;25(9):2295-303. doi: 10.1523/JNEUROSCI.5107-04.2005.
J Neurosci. 2005.
PMID: 15745955
Free PMC article.
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Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome.
Busciglio J, Pelsman A, Wong C, Pigino G, Yuan M, Mori H, Yankner BA.
Busciglio J, et al. Among authors: pelsman a.
Neuron. 2002 Feb 28;33(5):677-88. doi: 10.1016/s0896-6273(02)00604-9.
Neuron. 2002.
PMID: 11879646
Free article.
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GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons.
Pelsman A, Hoyo-Vadillo C, Gudasheva TA, Seredenin SB, Ostrovskaya RU, Busciglio J.
Pelsman A, et al.
Int J Dev Neurosci. 2003 May;21(3):117-24. doi: 10.1016/s0736-5748(03)00031-5.
Int J Dev Neurosci. 2003.
PMID: 12711349
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NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis.
Busciglio J, Pelsman A, Helguera P, Ashur-Fabian O, Pinhasov A, Brenneman DE, Gozes I.
Busciglio J, et al. Among authors: pelsman a.
Curr Pharm Des. 2007;13(11):1091-8. doi: 10.2174/138161207780618957.
Curr Pharm Des. 2007.
PMID: 17430172
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Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation.
Pigino G, Pelsman A, Mori H, Busciglio J.
Pigino G, et al. Among authors: pelsman a.
J Neurosci. 2001 Feb 1;21(3):834-42. doi: 10.1523/JNEUROSCI.21-03-00834.2001.
J Neurosci. 2001.
PMID: 11157069
Free PMC article.
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