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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 1
1987 2
1988 8
1989 5
1990 1
1991 5
1992 1
1993 3
1994 1
1995 10
1996 3
1997 1
1998 2
1999 2
2000 3
2001 5
2002 6
2003 6
2004 7
2005 11
2006 11
2007 4
2008 1
2009 5
2010 7
2011 2
2012 2
2013 2
2014 2
2015 5
2017 2
2018 1
2019 2
2020 3
2021 1
2023 1
2024 1

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124 results

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Page 1
A highly efficient transgene knock-in technology in clinically relevant cell types.
Allen AG, Khan SQ, Margulies CM, Viswanathan R, Lele S, Blaha L, Scott SN, Izzo KM, Gerew A, Pattali R, Cochran NR, Holland CS, Zhao AH, Sherman SE, Jaskolka MC, Wu M, Wilson AC, Sun X, Ciulla DM, Zhang D, Nelson JD, Zhang P, Mazzucato P, Huang Y, Giannoukos G, Marco E, Nehil M, Follit JA, Chang KH, Shearman MS, Wilson CJ, Zuris JA. Allen AG, et al. Among authors: shearman ms. Nat Biotechnol. 2024 Mar;42(3):458-469. doi: 10.1038/s41587-023-01779-8. Epub 2023 May 1. Nat Biotechnol. 2024. PMID: 37127662
Gamma-secretase inhibition.
Beher D, Shearman MS. Beher D, et al. Among authors: shearman ms. Biochem Soc Trans. 2002 Aug;30(4):534-7. doi: 10.1042/bst0300534. Biochem Soc Trans. 2002. PMID: 12196131 Review.
Protein kinase C family and nervous function.
Nishizuka Y, Shearman MS, Oda T, Berry N, Shinomura T, Asaoka Y, Ogita K, Koide H, Kikkawa U, Kishimoto A, et al. Nishizuka Y, et al. Among authors: shearman ms. Prog Brain Res. 1991;89:125-41. doi: 10.1016/s0079-6123(08)61719-7. Prog Brain Res. 1991. PMID: 1796138 Review. No abstract available.
Triazoles as γ-secretase modulators.
Fischer C, Zultanski SL, Zhou H, Methot JL, Brown WC, Mampreian DM, Schell AJ, Shah S, Nuthall H, Hughes BL, Smotrov N, Kenific CM, Cruz JC, Walker D, Bouthillette M, Nikov GN, Savage DF, Jeliazkova-Mecheva VV, Diaz D, Szewczak AA, Bays N, Middleton RE, Munoz B, Shearman MS. Fischer C, et al. Among authors: shearman ms. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4083-7. doi: 10.1016/j.bmcl.2011.04.089. Epub 2011 May 4. Bioorg Med Chem Lett. 2011. PMID: 21616665
Quinazolinones as γ-secretase modulators.
Fischer C, Shah S, Hughes BL, Nikov GN, Crispino JL, Middleton RE, Szewczak AA, Munoz B, Shearman MS. Fischer C, et al. Among authors: shearman ms. Bioorg Med Chem Lett. 2011 Jan 15;21(2):773-6. doi: 10.1016/j.bmcl.2010.11.111. Epub 2010 Nov 26. Bioorg Med Chem Lett. 2011. PMID: 21190851
The toxicity in vitro of beta-amyloid protein.
Iversen LL, Mortishire-Smith RJ, Pollack SJ, Shearman MS. Iversen LL, et al. Among authors: shearman ms. Biochem J. 1995 Oct 1;311 ( Pt 1)(Pt 1):1-16. doi: 10.1042/bj3110001. Biochem J. 1995. PMID: 7575439 Free PMC article. Review. No abstract available.
Potent benzoazepinone γ-secretase modulators with improved bioavailability.
Methot JL, Fischer C, Li C, Rivkin A, Ahearn SP, Brown WC, Kattar S, Kelley E, Mampreian DM, Schell A, Rosenau A, Zhou H, Ball R, Deshmukh SV, Jeliazkova-Mecheva VV, Diaz D, Moy LY, Kenific CM, Moxham C, Shah S, Nuthall H, Szewczak AA, Hill A, Hughes B, Smotrov N, Munoz B, Miller TA, Shearman MS. Methot JL, et al. Among authors: shearman ms. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3495-500. doi: 10.1016/j.bmcl.2015.06.032. Epub 2015 Jun 15. Bioorg Med Chem Lett. 2015. PMID: 26142947
The heterogeneity and differential expression of protein kinase C in nervous tissues.
Kikkawa U, Ogita K, Shearman MS, Ase K, Sekiguchi K, Naor Z, Ido M, Nishizuka Y, Saito N, Tanaka C, et al. Kikkawa U, et al. Among authors: shearman ms. Philos Trans R Soc Lond B Biol Sci. 1988 Jul 26;320(1199):313-24. doi: 10.1098/rstb.1988.0079. Philos Trans R Soc Lond B Biol Sci. 1988. PMID: 2906141 Review.
124 results