We previously demonstrated that sodium butyrate is neuroprotective in Huntington's disease
(HD) mice and that this therapeutic effect is associated with increased expression of mitogen…

Hippocalcin is a neuronal calcium sensor protein previously implicated in regulating neuronal
viability and plasticity. Hippocalcin is the most highly expressed neuronal calcium sensor …

Background This study was designed to describe patient, disease, and treatment characteristics
of women diagnosed with breast cancer at the Breast Examination Center of Harlem (…

Purpose: Enlarged perivascular spaces (EPVS) are brain MRI markers of subclinical small
vessel disease (SVD). Recent studies suggest that basal ganglia (BG) EPVS represent …

The precise cause of neuronal death in Huntington's disease (HD) is unknown. Although no
single specific protein-protein interaction of mutant huntingtin has emerged as the …

Having an extensive background in classical music performance and theory, as I began to
explore architecture, I immediately noticed profound similarities between the two art forms. …

The mitogen-activated protein kinase (MAPK) pathways are a group of conserved intracellular
signalling pathways present in most cells including neurons and glia. These pathways …

The mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in
the regulation of cell growth, proliferation, differentiation, transformation and death. Mitogen-…

Suckling buffalo calves were assigned at 7 days of age into four groups to receive milk
supplemented with no selenium (control), 0, 1, 0.2 and 0.3 ppm Se as groups 1, 2, 3 and 4, …

Decreases in the ratio of neurotrophic versus neurodegenerative signalling play a critical
role in Huntington’s disease (HD) pathogenesis and recent evidence suggests that the p75 …