User profiles for A. C. Nugent

Allison Nugent

NIH
Verified email at mail.nih.gov
Cited by 12614

Glutamate and gamma-aminobutyric acid systems in the pathophysiology of major depression and antidepressant response to ketamine

…, MJ Niciu, ED Ballard, M Park, LT Park, AC Nugent… - Biological …, 2017 - Elsevier
… of depressive symptoms was associated with increased metabolism in the PFC in groups
A and B, but not group C; whole-brain analysis confirmed a group effect on the PFC (group A<C

Grey matter differences in bipolar disorder: a meta‐analysis of voxel‐based morphometry studies

…, D Job, A Stanfield, TFD Farrow, AC Nugent… - Bipolar …, 2012 - Wiley Online Library
Selvaraj S, Arnone D, Job D, Stanfield A, Farrow TFD, Nugent AC, Scherk H, Gruber O,
Chen X, Sachdev PS, Dickstein DP, Malhi GS, Ha TH, Ha K, Phillips ML, McIntosh AM. Grey …

Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review

…, ED Ballard, NB Lundin, AC Nugent… - … advances in chronic …, 2015 - journals.sagepub.com
Current pharmacotherapies for major depressive disorder (MDD) and bipolar depression (BDep)
have a distinct lag of onset that can generate great distress and impairment in patients. …

Common genetic variants influence human subcortical brain structures

…, D Reese McKay, M Needham, AC Nugent… - Nature, 2015 - nature.com
The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …

[HTML][HTML] Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

…, D Mataix-Cols, AM McIntosh, AC Nugent… - Molecular …, 2017 - nature.com
Finding robust brain substrates of mood disorders is an important target for research. The
degree to which major depression (MDD) and bipolar disorder (BD) are associated with …

Identification of common variants associated with human hippocampal and intracranial volumes

…, S Mohnke, SM Maniega, K Nho, AC Nugent… - Nature …, 2012 - nature.com
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

Reduced serotonin type 1A receptor binding in panic disorder

A Neumeister, E Bain, AC Nugent… - Journal of …, 2004 - Soc Neuroscience
Recent animal models suggest that disturbances in serotonin type-1A receptor (5-HT 1A R)
function may contribute to chronic anxiety, although it is not clear at all whether such models …

Reduced hippocampal volume in unmedicated, remitted patients with major depression versus control subjects

A Neumeister, S Wood, O Bonne, AC Nugent… - Biological …, 2005 - Elsevier
BACKGROUND: Hippocampal volumes obtained from a group of medication-free, remitted
subjects with recurrent major depressive disorder (MDD) were compared against …

Neural and behavioral responses to tryptophan depletion in unmedicatedpatients with remitted major depressive disorder and controls

A Neumeister, AC Nugent, T Waldeck… - Archives of general …, 2004 - jamanetwork.com
Context An instructive paradigm for investigating the relationship between brain serotonin
function and major depressive disorder (MDD) is the response to tryptophan depletion (TD) …

[HTML][HTML] Novel genetic loci associated with hippocampal volume

…, S Muñoz Maniega, K Nho, AC Nugent… - Nature …, 2017 - nature.com
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …