The basal ganglia network serves to integrate information about context, actions, and outcomes
to shape the behavior of an animal based on its past experience. Clinically, the basal …

The development of methodology to identify specific cell populations and circuits within the
basal ganglia is rapidly transforming our ability to understand the function of this complex …

The vestibular system provides an attractive model for understanding how changes in
cellular and synaptic activity influence learning and memory in a quantifiable behavior, the …

Striatal GABAergic microcircuits are critical for motor function, yet their properties remain
enigmatic due to difficulties in targeting striatal interneurons for electrophysiological analysis. …

Symptoms of neurological diseases emerge through the dysfunction of neural circuits
whose diffuse and intertwined architectures pose serious challenges for delivering therapies. …

Fast-spiking interneurons (FSIs) can exert powerful control over striatal output, and deficits
in this cell population have been observed in human patients with Tourette syndrome and …

In Parkinson's disease (PD), dopamine depletion alters neuronal activity in the direct and
indirect pathways and leads to increased synchrony in the basal ganglia network. However, …

The neurotransmitter glutamate is released by excitatory projection neurons throughout the
brain. However, non-glutamatergic cells, including cholinergic and monoaminergic neurons, …

Cell-type diversity in the brain enables the assembly of complex neural circuits, whose
organization and patterns of activity give rise to brain function. However, the identification of …

The identification of distinct cell types in the basal ganglia has been critical to our understanding
of basal ganglia function and the treatment of neurological disorders. The external …