Objective: Our objective was to evaluate the published literature and reach a consensus on
the treatment of patients with ACTH-dependent Cushing’s syndrome, because there is no …

Context: There is growing interest in the relationship between bone mineral density, bone
strength, and fat depots. Marrow adipose tissue, a well-established component of the marrow …

A 42-year-old man presents with decreased libido, erectile dysfunction, and headaches. He
reports no weight change, gynecomastia, fatigue, or other symptoms. He takes no …

Meningiomas are common tumors, representing 15% to 25% of all central nervous system
tumors. NF2 gene inactivation on chromosome 22 has been shown as an early event in …

Objectives: To clarify the factors associated with prevention, diagnosis, and treatment of
osteoporosis, and to present the most recent information available in these areas. Participants: …

Background Patients with acromegaly are treated with surgery, radiation therapy, and drugs
to reduce hypersecretion of growth hormone, but the treatments may be ineffective and have …

Acquired hypogonadism is being increasingly recognized in adult men. However, the effects
of long term testosterone replacement on bone density and body composition are largely …

The adipocyte-derived hormone adiponectin promotes metabolic and cardiovascular health.
Circulating adiponectin increases in lean states such as caloric restriction (CR), but the …

Clinically nonfunctioning pituitary adenomas are benign neoplasms comprising approximately
25-30% of pituitary tumors. Little is known about the pathogenesis of pituitary neoplasia. …

To analyze the long term outcome after multimodality therapy for acromegaly, a retrospective
review was performed on 162 patients who underwent transsphenoidal surgery at …