Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex
A Misko, S Jiang, I Wegorzewska… - Journal of …, 2010 - Soc Neuroscience
Mitofusins (Mfn1 and Mfn2) are outer mitochondrial membrane proteins involved in
regulating mitochondrial dynamics. Mutations in Mfn2 cause Charcot-Marie-Tooth disease (CMT) …
regulating mitochondrial dynamics. Mutations in Mfn2 cause Charcot-Marie-Tooth disease (CMT) …
Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration
AL Misko, Y Sasaki, E Tuck, J Milbrandt… - Journal of …, 2012 - Soc Neuroscience
Alterations in mitochondrial dynamics (fission, fusion, and movement) are implicated in
many neurodegenerative diseases, from rare genetic disorders such as Charcot-Marie-Tooth …
many neurodegenerative diseases, from rare genetic disorders such as Charcot-Marie-Tooth …
Taxonomic and functional diversity of pseudomonads isolated from the roots of field-grown canola
AL Misko, JJ Germida - FEMS Microbiology Ecology, 2002 - academic.oup.com
Among the most important rhizosphere bacteria are the pseudomonads, which are aggressive
colonizers and utilize a wide range of substrates as carbon sources. The objective of this …
colonizers and utilize a wide range of substrates as carbon sources. The objective of this …
[HTML][HTML] The role of glutamate oxaloacetate transaminases in sulfite biosynthesis and H2S metabolism
Molybdenum cofactor deficiency and isolated sulfite oxidase deficiency are two rare genetic
disorders that are caused by impairment of the mitochondrial enzyme sulfite oxidase. Sulfite …
disorders that are caused by impairment of the mitochondrial enzyme sulfite oxidase. Sulfite …
Candidate genes of cuticle formation show characteristic expression in the fruit skin of apple
Z Albert, B Ivanics, A Molnár, A Miskó, M Tóth… - Plant Growth …, 2013 - Springer
Based on the Arabidopsis model of production and transport of cuticular components in
silico analysis of apple EST and genomic sequences identified candidate genes potentially …
silico analysis of apple EST and genomic sequences identified candidate genes potentially …
Matrix metalloproteinase mediated degradation of basement membrane proteins in Trembler J neuropathy nerves
A Misko, T Ferguson, L Notterpek - Journal of neurochemistry, 2002 - Wiley Online Library
A single point mutation in peripheral myelin protein 22 (pmp22) of the Trembler‐J (TrJ)
mouse models the human peripheral neuropathy, Charcot–Marie–Tooth disease type 1 A (…
mouse models the human peripheral neuropathy, Charcot–Marie–Tooth disease type 1 A (…
Delineating the phenotypic spectrum of sulfite oxidase and molybdenum cofactor deficiency
AL Misko, Y Liang, JB Kohl, F Eichler - Neurology: Genetics, 2020 - AAN Enterprises
Objective To define the phenotypic spectrum of isolated sulfite oxidase (ISOD) and molybdenum
cofactor deficiency (MoCD), aiming to promote timely diagnosis and assist in future …
cofactor deficiency (MoCD), aiming to promote timely diagnosis and assist in future …
[HTML][HTML] Progress in elucidating pathophysiology of mucolipidosis IV
Mucolipidosis IV (MLIV) is an autosomal-recessive disease caused by loss-of-function mutations
in the MCOLN1 gene encoding the non-selective cationic lysosomal channel transient …
in the MCOLN1 gene encoding the non-selective cationic lysosomal channel transient …
MCOLN1 gene therapy corrects neurologic dysfunction in the mouse model of mucolipidosis IV
…, S Slaugenhaupt, A Misko… - Human Molecular …, 2021 - academic.oup.com
Mucolipidosis IV (MLIV) is an orphan disease leading to debilitating psychomotor deficits
and vision loss. It is caused by loss-of-function mutations in the MCOLN1 gene that encodes …
and vision loss. It is caused by loss-of-function mutations in the MCOLN1 gene that encodes …
[HTML][HTML] Sulfite alters the mitochondrial network in molybdenum cofactor deficiency
AT Mellis, J Roeper, AL Misko, J Kohl… - Frontiers in …, 2021 - frontiersin.org
Molybdenum cofactor deficiency (MoCD) is an autosomal recessive disorder belonging to the
large family of inborn errors in metabolism. Patients typically present with encephalopathy …
large family of inborn errors in metabolism. Patients typically present with encephalopathy …