Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction

S Martin, KA Wilkinson, A Nishimune… - Nature Reviews …, 2007 - nature.com
Post-translational protein modifications are integral components of signalling cascades that
enable cells to efficiently, rapidly and reversibly respond to extracellular stimuli. These …

[PDF][PDF] NSF binding to GluR2 regulates synaptic transmission

A Nishimune, JTR Isaac, E Molnar, J Noel, SR Nash… - Neuron, 1998 - cell.com
Here, we show that N-ethylmaleimide–sensitive fusion protein (NSF) interacts directly and
selectively with the intracellular C-terminal domain of the GluR2 subunit of AMPA receptors. …

Lateral diffusion drives constitutive exchange of AMPA receptors at dendritic spines and is regulated by spine morphology

MC Ashby, SR Maier, A Nishimune… - Journal of …, 2006 - Soc Neuroscience
Synapse specificity is a basic feature of synaptic plasticity, but it remains unclear how
synapse-specific signaling is achieved if postsynaptic membrane proteins can diffuse laterally …

SUMOylation regulates kainate-receptor-mediated synaptic transmission

S Martin, A Nishimune, JR Mellor, JM Henley - Nature, 2007 - nature.com
The small ubiquitin-like modifier protein (SUMO) regulates transcriptional activity and the
translocation of proteins across the nuclear membrane 1 . The identification of SUMO …

The protein kinase Cα binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits

KK Dev, A Nishimune, JM Henley, S Nakanishi - Neuropharmacology, 1999 - Elsevier
Here we report an interaction between AMPA receptor subunits and a single PDZ domain-containing
protein called PICK1 which is known to bind protein kinase Cα (PKCα). The …

[HTML][HTML] The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes: analysis of PDZ binding motifs

H Hirbec, O Perestenko, A Nishimune, G Meyer… - Journal of Biological …, 2002 - ASBMB
Using sequence homology searches, yeast two-hybrid assays and glutathione S-transferase
(GST)-pull-down approaches we have identified a series of glutamate receptor subunits …

Regional quantification of muscarinic acetylcholine receptors and β‐adrenoceptors in human airways

…, T Koshiji, J Uwada, A Nishimune… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE Muscarinic acetylcholine receptors (mAChRs) and β‐adrenoceptors
in the airways and lungs are clinically important in chronic obstructive pulmonary …

Protein SUMOylation modulates calcium influx and glutamate release from presynaptic terminals

M Feligioni, A Nishimune… - European Journal of …, 2009 - Wiley Online Library
Posttranslational modification by small ubiquitin‐like modifier (SUMO) proteins is emerging
as an important regulatory mechanism for neuronal function and dysfunction. Although …

Radiological impact of TEPCO's Fukushima Dai-ichi Nuclear Power Plant accident on invertebrates in the coastal benthic food web

…, T Mizuno, Y Nemoto, S Igarashi, A Nishimune… - Journal of environmental …, 2014 - Elsevier
Radioactive cesium ( 134 Cs and 137 Cs) concentrations in invertebrates of benthic food web
(10 taxonomic classes with 46 identified families) collected from wide areas off Fukushima …

Competitive interaction of Seven in absentia homolog‐1A and Ca2+/calmodulin with the cytoplasmic tail of group 1 metabotropic glutamate receptors

K Ishikawa, SR Nash, A Nishimune, A Neki… - Genes to …, 1999 - Wiley Online Library
Background Group 1 metabotropic glutamate receptors (mGluR1 and mGluR5) are coupled
to inositol trisphosphate/Ca 2+ signaling via G proteins and play an important role in …