Introduction Older adults are generally considered to be at greater risk for medication non-adherence
due to factors such as medication complexity, side effects, cost, and cognitive …

Introduction: Benzodiazepines (BZD) are potentially inappropriate for older adults, yet their
use persists. Patients and providers may hesitate to discontinue BZDs due to concerns for …

Increasing evidence indicates that development of embryonic central nervous system
precursors is tightly regulated by extrinsic cues located in the local environment. Here, we asked …

Antiviral immunity requires early and late mechanisms in which IFN-α and IL-12 play major
roles. However, the initial events leading to their production remain largely unclear. Given the …

High rates of APOBEC-signature mutations are found in many tumors, but factors affecting
this mutation pattern are not well understood. Here we explored the contribution of two …

Do people have insight into the validity of their first impressions or accuracy awareness?
Across two large interactive round-robins, those who reported having formed a more accurate …

Frain the Department of Surgery (Urology) of the Cornell University M. edical College: and
the Department of Surgery (Urology), James Buchanan Brady Foundation, of the New York …

Microglia play important roles in the damaged or degenerating adult nervous system.
However, the role of microglia in embryonic brain development is still largely uncharacterized. …

Mammalian neurogenesis is determined by an interplay between intrinsic genetic mechanisms
and extrinsic cues such as growth factors. Here we have defined a signaling cascade, a …

Objective The aim of this study was to assess the impact of sex on the management and
outcome of patients according to aortic stenosis (AS) severity. Introduction Sex differences in the …