Neurodegenerative, inflammatory and neoplastic brain disorders involve neuroinflammatory
reactions, and a biomarker of neuroinflammation would be useful for diagnostic, drug …

… Monoamine oxidase type B is an enzyme located at the outer mitochondrial membrane
primarily in astrocytes and serotoninergic neurons. Monoamine oxidase type B catalyzes the …

Oligonucleotides are multifunctional molecules which can interfere with gene expression by
different mechanism such as antisense, RNA interference, ribozymes, etc. For most in vivo …

… In this equation, the left hand side is the flow of configurations a transformed into configurations
b, while the right hand side corresponds to the reverse flow from b to a. In practice, it is …

… Solvent A was 0.1% aqueous trifluoroacetic acid, solvent B was CH 3 CN, gradient elution
(A/B) was 80:20 to 20:80 in 10 min, followed by 5 min at 20:80, flow rate was 4 mL/min, and …

… Cells were either left unstimulated (A), stimulated with GDNF (B), or with GDNF together
with D4 or D4Sc (C and D, respectively). Following 48 h of GDNF treatment, the percentage of …

The association between altered gut microbiota, intestinal permeability, inflammation and
cardiometabolic diseases is becoming increasingly clear but remains poorly understood 1 , 2 . …

Focal cerebral ischemia leads to an inflammatory reaction involving an overexpression of
the peripheral benzodiazepine receptor (PBR)/18-kDa translocator protein (TSPO) in the …

The data reported in this study show (1) that the proposed radiolabelling methods does not
modify the capcity of the antisense oligonucleotide to hybridize to its target complemetary …

… In ipsilateral side, intense microglial activation (red) was observed within lesion core
surrounded by a clear astroglial activation (green) (delineated by dashed arrows in B), whereas …