High-fat diet (HFD)-induced obesity is associated with not only increased risk of metabolic
and cardiovascular diseases, but cognitive deficit, depression and anxiety disorders. Obesity …

Traumatic brain injury (TBI) is a major public health concern affecting a large number of athletes
and military personnel. Individuals suffering from a TBI risk developing anxiety disorders…

Patients that suffer mild traumatic brain injuries (mTBI) often develop cognitive impairments,
including memory and learning deficits. The hippocampus shows a high susceptibility to …

Background: Differences in the composition of control diets may confound outcomes in
studies investigating dietary effects. Objective: We compared the effects of two control diets …

Kainate receptors containing the GluK1 subunit (GluK1Rs; previously known as GluR5 kainate
receptors) are concentrated in certain brain regions, where they play a prominent role in …

The discovery that even small changes in extracellular acidity can alter the excitability of
neuronal networks via activation of acid-sensing ion channels (ASICs) could have therapeutic …

Organophosphorus nerve agents are powerful neurotoxins that irreversibly inhibit
acetylcholinesterase (AChE) activity. One of the consequences of AChE inhibition is the generation …

Mild traumatic brain injury (mTBI) often has long-term effects on cognitive function and social
behavior. Altered gene expression may be predictive of long-term psychological effects of …

Exposure to nerve agents induces intense seizures (status epilepticus, SE), which cause
brain damage or death. Identification of the brain regions that are critical for seizure initiation …

Inhibition of acetylcholinesterase (AChE) after nerve agent exposure induces status
epilepticus (SE), which causes brain damage or death. The development of countermeasures …