User profiles for C. Drummond-Main

Chris Drummond-Main

Research Associate, University of Calgary
Verified email at ucalgary.ca
Cited by 714

Systematic review of nondermatophyte mold onychomycosis: diagnosis, clinical types, epidemiology, and treatment

AK Gupta, C Drummond-Main, EA Cooper… - Journal of the American …, 2012 - Elsevier
… Cultures are grown for a period ranging from 7 days to 6 weeks, at temperatures between
25C and 37C. The resulting colonies are identified by microscopic and macroscopic details, …

Meta‐analysis of randomized, controlled trials comparing particular doses of griseofulvin and terbinafine for the treatment of tinea capitis

AK Gupta, C DrummondMain - Pediatric Dermatology, 2013 - Wiley Online Library
Two oral antifungal agents, griseofulvin and terbinafine, have regulatory approval in the
United States, but it is unknown whether one has superior overall efficacy. Genus‐specific …

Evidence-based optimal fluconazole dosing regimen for onychomycosis treatment

AK Gupta, C Drummond-Main… - Journal of dermatological …, 2013 - Taylor & Francis
Background: Fluconazole could be an alternative to terbinafine and itraconazole for
onychomycosis treatment. However, it is difficult to determine the optimal dosing regimen due to the …

Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis

…, B Fuerth, P Swan, C Drummond-Main… - Journal of …, 2007 - Soc Neuroscience
Oxidative stress has been implicated as a key trigger of neuronal apoptosis in stroke and
neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and …

[HTML][HTML] Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels

SC Stotz, LOM Scott, C Drummond-Main… - Molecular brain, 2014 - Springer
Background Inorganic polyphosphate (polyP) is a highly charged polyanion capable of
interacting with a number of molecular targets. This signaling molecule is released into the …

[HTML][HTML] High dose folic acid supplementation of rats alters synaptic transmission and seizure susceptibility in offspring

…, J Harris, S Iannattone, C Drummond-Main… - Scientific reports, 2013 - nature.com
Maternal folic acid supplementation is essential to reduce the risk of neural tube defects. We
hypothesize that high levels of folic acid throughout gestation may produce neural networks …

Cannabidiol impairs brain mitochondrial metabolism and neuronal integrity

CD Drummond-Main, Y Ahn, M Kesler… - Cannabis and …, 2023 - liebertpub.com
Background: The mechanisms underlying the clinical effects of CBD remain poorly understood.
Given the increasing evidence for CBD's effects on mitochondria, we sought to examine …

[PDF][PDF] Cannabidiol counters the effects of a dominant-negative pathogenic Kv7. 2 variant

X Zhan, C Drummond-Main, D Greening, J Yao… - Iscience, 2022 - cell.com
… when evoked with the protocol shown in (C). Sample numbers are shown in brackets. … (C)
Quantification of the change of EGFP intensity under different expression combinations shows …

Residency duration and shelter quality influence vibratory signalling displays in a territorial caterpillar

JE Yack, S Gill, C DrummondMain, TN Sherratt - Ethology, 2014 - Wiley Online Library
Residents are more likely to win territorial disputes than intruders. One explanation for this
prior resident advantage is that residents place a higher value on the resource and are …

Electrophysiological characterization of a mitochondrial inner membrane chloride channel in rat brain

CD DrummondMain, JM Rho - FEBS letters, 2018 - Wiley Online Library
… chloride channel in rat brain - DrummondMain - 2018 - FEBS Letters - Wiley Online Library
… centrifuged at 175 000 × g for 30 min at 4 C. The resulting pellets were rinsed with 1 mL of …