… Moreover, under the same conditions, the contribution of loops A and B from the `principal
component' of the α-subunits increases up to six-fold relative to loop C, a finding consistent …

The sense of smell significantly contributes to quality of life. In recent years much progress
has been made in understanding the biochemistry, physiology and pathology of the human …

Release of the neurotransmitter dopamine in the mesolimbic system of the brain mediates the
reinforcing properties of several drugs of abuse, including nicotine 1 . Here we investigate …

… : cAMPdependent kinase (PKA); protein kinase C (PKC), which also phosphorylates the …
(C) Ca 2+ increases singlechannel opening frequency in outside-out recordings (adapted …

… f2" heterozygotes were mated and offspring were evaluated by PCR analysis (b), b, PCR
was 35 cycles of 94 C for 1 min, 65 C for 2 min and 72 C for 1 min. c, Southern blotting was as …

… Incubation was prolonged overnight at 4C. Nonspecific binding was measured in the
presence of 100 nm unlabeled Epi. For each ligand, data from three to six experiments were …

… c, Western blot analysis of total brain extracts using a polyclonal antibody against α4 subunit
(MMA-J. et … cDNA was amplified for 35 cycles of one minute at each of 96 C, 60 C and 72 C. …

… (c) Cell surface staining for CD8α and GFP on gated CD45 + TCRβ + CD8β − CD4 + IELs
as in b. Numbers in quadrants indicate percent cells in each throughout. (d) Cell surface …

… , all performed at 4C. Nonspecific binding was defined … 4C. It was followed by two rinses of
2 min in 50 mm Tris-HCl, pH 7.4, followed by a brief rinse in distilled water, all performed at 4C…

Brain activity in sleep plays a crucial role in memory consolidation, an offline process that
determines the long-term strength of memory traces. Consolidation efficacy differs across …