The dendritic trees of neurons are structurally and functionally complex integrative units
receiving thousands of synaptic inputs that have excitatory and inhibitory, fast and slow, and …

We report the application of single-molecule-based sequencing technology for high-throughput
profiling of histone modifications in mammalian cells. By obtaining over four billion bases …

The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements
in the human genome sequence. The pilot phase of the Project is focused on a specified …

DNA methylation is essential for normal development 1 , 2 , 3 and has been implicated in
many pathologies including cancer 4 , 5 . Our knowledge about the genome-wide distribution …

Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris),
together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The …

Massively parallel DNA sequencing technologies are revolutionizing genomics by making it
possible to generate billions of relatively short (~100-base) sequence reads at very low cost. …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Targeting genomic loci by massively parallel sequencing requires new methods to enrich
templates to be sequenced. We developed a capture method that uses biotinylated RNA 'baits' …

… WM were responsible for gene model refinement, database design and database maintenance;
GM, J. Kämper, RK, GS, M. Feldbrügge, JS, CWB, UF, MB, BS, BJS, MJC, ECHH, SM, FB…

… , “K-mer Numbering and Database”). The unipaths can then … interval in the K-mer path
database the K-mer number before and … We proceed forward through the database looking for …