Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo
…, MR Kelley, L Silayeva, DH Morrow… - Journal of …, 2015 - Soc Neuroscience
GABA A receptors form Cl − permeable channels that mediate the majority of fast synaptic
inhibition in the brain. The K + /Cl − cotransporter KCC2 is the main mechanism by which …
inhibition in the brain. The K + /Cl − cotransporter KCC2 is the main mechanism by which …
Calculation of ATP production rates using the Seahorse XF Analyzer
…, AE Jones, AB Ball, WY Hsieh, P Swain, DH Morrow… - EMBO …, 2023 - embopress.org
Oxidative phosphorylation and glycolysis are the dominant ATP‐generating pathways in
mammalian metabolism. The balance between these two pathways is often shifted to execute …
mammalian metabolism. The balance between these two pathways is often shifted to execute …
The small molecule CLP257 does not modify activity of the K+–Cl− co-transporter KCC2 but does potentiate GABAA receptor activity
…, I Chudotvorova, J Guyot, L Silayeva, DH Morrow… - Nature Medicine, 2017 - nature.com
METHODS Methods, including statements of data availability and any associated accession
codes and references, are available in the online version of the paper.
codes and references, are available in the online version of the paper.
[HTML][HTML] Proteomic characterization of inhibitory synapses using a novel pHluorin-tagged γ-aminobutyric acid receptor, type A (GABAA), α2 subunit knock-in mouse
Y Nakamura, DH Morrow, A Modgil, D Huyghe… - Journal of Biological …, 2016 - ASBMB
The accumulation of γ-aminobutyric acid receptors (GABA A Rs) at the appropriate postsynaptic
sites is critical for determining the efficacy of fast inhibitory neurotransmission. Although …
sites is critical for determining the efficacy of fast inhibitory neurotransmission. Although …
Post-caesarean section analgesia: a comparison of epidural butorphanol and morphine
…, KR Hess, BS Skjonsby, DH Morrow… - Canadian journal of …, 1991 - Springer
Epidural butorphanol 1, 2 and 4 mg were compared with morphine, 5 mg, for postoperative
analgesia in 92 consenting, healthy, term parturients who had undergone Caesarean section …
analgesia in 92 consenting, healthy, term parturients who had undergone Caesarean section …
Amine‐weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors
…, BR Desousa, A Divakaruni, DH Morrow… - NMR in …, 2023 - Wiley Online Library
Amine‐weighted chemical exchange saturation transfer (CEST) magnetic resonance imaging
(MRI) is particularly valuable as an amine‐ and pH‐sensitive imaging technique in brain …
(MRI) is particularly valuable as an amine‐ and pH‐sensitive imaging technique in brain …
Chronic Intermittent Ethanol Exposure and Withdrawal Alters (3α,5α)‐3‐Hydroxy‐Pregnan‐20‐One Immunostaining in Cortical and Limbic Brain Regions of C57BL …
…, JB Cook, TK O'Buckley, DH Morrow… - Alcoholism: Clinical …, 2014 - Wiley Online Library
Background The GABA ergic neuroactive steroid (3α,5α)‐3‐hydroxy‐pregnan‐20‐one (3α,5α‐
THP ; allopregnanolone) has been studied during withdrawal from ethanol (EtOH) in …
THP ; allopregnanolone) has been studied during withdrawal from ethanol (EtOH) in …
[PDF][PDF] Studies on digitalis. VIII. Effect of autonomic innervation and of myocardial catecholamine stores upon the cardiac action of ouabain
DH Morrow, TE Gaffney, E Braunwald - Journal of Pharmacology and …, 1963 - Citeseer
METHODS. A total of 56 experiments was performed in five types of preparations. There
were 17 control dogs and 8 animals in which bilateral cervical vagotomy was performed just …
were 17 control dogs and 8 animals in which bilateral cervical vagotomy was performed just …
[HTML][HTML] “Aerobic glycolytic imaging” of human gliomas using combined pH-, oxygen-, and perfusion-weighted magnetic resonance imaging
Purpose To quantify abnormal metabolism of diffuse gliomas using “aerobic glycolytic
imaging” and investigate its biological correlation. Methods All subjects underwent a pH-weighted …
imaging” and investigate its biological correlation. Methods All subjects underwent a pH-weighted …
[HTML][HTML] Chronic intermittent ethanol exposure alters stress effects on (3α, 5α)-3-hydroxy-pregnan-20-one (3α, 5α-THP) immunolabeling of amygdala neurons in …
…, DH Morrow, TK O'Buckley, AL Morrow - Frontiers in cellular …, 2016 - frontiersin.org
The GABAergic neuroactive steroid (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP,
allopregnanolone) is decreased in various brain regions of C57BL/6J mice following exposure to an …
allopregnanolone) is decreased in various brain regions of C57BL/6J mice following exposure to an …