Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo

…, MR Kelley, L Silayeva, DH Morrow… - Journal of …, 2015 - Soc Neuroscience
GABA A receptors form Cl − permeable channels that mediate the majority of fast synaptic
inhibition in the brain. The K + /Cl − cotransporter KCC2 is the main mechanism by which …

Calculation of ATP production rates using the Seahorse XF Analyzer

…, AE Jones, AB Ball, WY Hsieh, P Swain, DH Morrow… - EMBO …, 2023 - embopress.org
Oxidative phosphorylation and glycolysis are the dominant ATP‐generating pathways in
mammalian metabolism. The balance between these two pathways is often shifted to execute …

The small molecule CLP257 does not modify activity of the K+–Cl co-transporter KCC2 but does potentiate GABAA receptor activity

…, I Chudotvorova, J Guyot, L Silayeva, DH Morrow… - Nature Medicine, 2017 - nature.com
METHODS Methods, including statements of data availability and any associated accession
codes and references, are available in the online version of the paper.

[HTML][HTML] Proteomic characterization of inhibitory synapses using a novel pHluorin-tagged γ-aminobutyric acid receptor, type A (GABAA), α2 subunit knock-in mouse

Y Nakamura, DH Morrow, A Modgil, D Huyghe… - Journal of Biological …, 2016 - ASBMB
The accumulation of γ-aminobutyric acid receptors (GABA A Rs) at the appropriate postsynaptic
sites is critical for determining the efficacy of fast inhibitory neurotransmission. Although …

Post-caesarean section analgesia: a comparison of epidural butorphanol and morphine

…, KR Hess, BS Skjonsby, DH Morrow… - Canadian journal of …, 1991 - Springer
Epidural butorphanol 1, 2 and 4 mg were compared with morphine, 5 mg, for postoperative
analgesia in 92 consenting, healthy, term parturients who had undergone Caesarean section …

Amine‐weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors

…, BR Desousa, A Divakaruni, DH Morrow… - NMR in …, 2023 - Wiley Online Library
Amine‐weighted chemical exchange saturation transfer (CEST) magnetic resonance imaging
(MRI) is particularly valuable as an amine‐ and pH‐sensitive imaging technique in brain …

Chronic Intermittent Ethanol Exposure and Withdrawal Alters (3α,5α)‐3‐Hydroxy‐Pregnan‐20‐One Immunostaining in Cortical and Limbic Brain Regions of C57BL …

…, JB Cook, TK O'Buckley, DH Morrow… - Alcoholism: Clinical …, 2014 - Wiley Online Library
Background The GABA ergic neuroactive steroid (3α,5α)‐3‐hydroxy‐pregnan‐20‐one (3α,5α‐
THP ; allopregnanolone) has been studied during withdrawal from ethanol (EtOH) in …

[PDF][PDF] Studies on digitalis. VIII. Effect of autonomic innervation and of myocardial catecholamine stores upon the cardiac action of ouabain

DH Morrow, TE Gaffney, E Braunwald - Journal of Pharmacology and …, 1963 - Citeseer
METHODS. A total of 56 experiments was performed in five types of preparations. There
were 17 control dogs and 8 animals in which bilateral cervical vagotomy was performed just …

[HTML][HTML] “Aerobic glycolytic imaging” of human gliomas using combined pH-, oxygen-, and perfusion-weighted magnetic resonance imaging

…, NS Cho, R Everson, K Patel, DH Morrow… - NeuroImage: Clinical, 2021 - Elsevier
Purpose To quantify abnormal metabolism of diffuse gliomas using “aerobic glycolytic
imaging” and investigate its biological correlation. Methods All subjects underwent a pH-weighted …

[HTML][HTML] Chronic intermittent ethanol exposure alters stress effects on (3α, 5α)-3-hydroxy-pregnan-20-one (3α, 5α-THP) immunolabeling of amygdala neurons in …

…, DH Morrow, TK O'Buckley, AL Morrow - Frontiers in cellular …, 2016 - frontiersin.org
The GABAergic neuroactive steroid (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP,
allopregnanolone) is decreased in various brain regions of C57BL/6J mice following exposure to an …