Fates and migratory routes of primitive streak cells in the chick embryo

D Psychoyos, CD Stern - Development, 1996 - journals.biologists.com
We have used carbocyanine dyes to fate map the primitive streak in the early chick embryo,
from stages 3 + (mid-primitive streak) to 9 (8 somites). We show that presumptive notochord, …

G9a-mediated histone methylation regulates ethanol-induced neurodegeneration in the neonatal mouse brain

…, A Kumar, RA Nixon, AD Verin, D Psychoyos… - Neurobiology of …, 2013 - Elsevier
Rodent exposure to binge-like ethanol during postnatal day 7 (P7), which is comparable to
the third trimester of human pregnancy, induces neuronal cell loss. However, the molecular …

[HTML][HTML] Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats

KY Vinod, S Xie, D Psychoyos, BL Hungund… - PloS one, 2012 - journals.plos.org
Background While the etiology of depression is not clearly understood at the present time,
this mental disorder is thought be a complex and multifactorial trait with important genetic and …

Anandamide–CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits

S Subbanna, M Shivakumar, D Psychoyos… - Journal of …, 2013 - Soc Neuroscience
… Mice were kept with the dams until the pups were killed, and their brains were removed 4–24
h or 90 d after the first saline/ethanol injection. The brains were processed for several …

Marijuana, Spice 'herbal high', and early neural development: implications for rescheduling and legalization

D Psychoyos, KY Vinod - Drug testing and analysis, 2013 - Wiley Online Library
… The synthesis of AEA occurs mainly by NAPE-specific phospholipase D (NAPE-PLD) and
it … of 18–22 weeks gestation (Figure 4C,D).193 It is possible that defective dopamine D2 …

CB 1‐receptor knockout neonatal mice are protected against ethanol‐induced impairments of DNMT 1, DNMT 3A, and DNA methylation

…, M Shivakumar, D Psychoyos… - Journal of …, 2015 - Wiley Online Library
… (d) Global DNA methylation quantification in hippocampal (HP) and neocortical (NC) DNA
obtained 4–24 h … 3d). We found reduced DNMT3A mRNA levels in the hippocampus (F 3,28 …

Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice

…, M Shivakumar, NS Umapathy, D Psychoyos… - Neuroscience, 2014 - Elsevier
The transient exposure of immature rodents to ethanol during postnatal day 7 (P7), comparable
to a time point within the third trimester of human pregnancy, induces neurodegeneration…

Restoration of the organizer after radical ablation of Hensen's node and the anterior primitive streak in the chick embryo

D Psychoyos, CD Stern - Development, 1996 - journals.biologists.com
The region of the amniote embryo corresponding to Spemann’s organizer in amphibians is
Hensen’s node, which lies at the tip of the primitive streak during gastrulation. It is a special …

Cannabinoid receptor 1 signaling in embryo neurodevelopment

D Psychoyos, KY Vinod, J Cao, S Xie… - … Research Part B …, 2012 - Wiley Online Library
… expression of CB 1 mRNA in Hensen's node from embryos at stages ranging from 3 + to 8
− , using the same fate maps as described above, as well as the fate maps from Psychoyos

[HTML][HTML] CB1R-mediated activation of caspase-3 causes epigenetic and neurobehavioral abnormalities in postnatal ethanol-exposed mice

…, M Shivakumar, V Joshi, D Psychoyos… - Frontiers in molecular …, 2018 - frontiersin.org
Alcohol exposure can affect brain development, leading to long-lasting behavioral problems,
including cognitive impairment, which together is defined as fetal alcohol spectrum disorder …