Cytokines are constitutively released in the healthy brain by resident myeloid cells to keep
proper synaptic plasticity, either in the form of Hebbian synaptic plasticity or of homeostatic …

Aging is one of the main risk factors for the development of many neurodegenerative
diseases. Emerging evidence has acknowledged neuroinflammation as potential trigger of the …

Studies of brain network connectivity improved understanding on brain changes and adaptation
in response to different pathologies. Synaptic plasticity, the ability of neurons to modify …

… This analysis revealed a significant main effect of group of treatment (F = 5.92; P < .05) and
a significant GROUP × TIME interaction (F = 3.47; P < .05) (Fig 1B). Post hoc comparisons …

It has long been known that multiple sclerosis (MS) is associated with an increased Epstein-Barr
virus (EBV) seroprevalence and high immune reactivity to EBV and that infectious …

… (f) The electrophysiological traces are examples of sEPSCs recorded from striatal neurons in
the … (f) The graph shows that etanercept attenuated the neurotoxic effects of CSF from PMS …

… between BMI group and leptin CSF levels (on logarithmic scale) adjusting for sex, age,
disease duration, smoking, and the presence of radiological activity (ANCOVA main effect: F(2, …

… CP) as between subjects main factors showed a significant effect of time (F=8.04, p=0.002),
a significant effect of GROUP (F=6.82, p=0.023) and a significant TIME × GROUP interaction (…

Regulatory T Cells (Tregs) are a T-lymphocyte subset involved in the maintenance of immune
peripheral tolerance. Despite evidence of the adaptive immune system’s role in Alzheimer’…

Background Understanding how inflammation causes neuronal damage is of paramount
importance in multiple sclerosis (MS) and in other neurodegenerative diseases. Here we …