Diversity of native nicotinic receptor subtypes in mammalian brain

M Zoli, F Pistillo, C Gotti - Neuropharmacology, 2015 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a heterogeneous family of pentameric
ligand-gated cation channels that are expressed throughout the brain and involved in a …

Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects

F Pistillo, F Clementi, M Zoli, C Gotti - Progress in neurobiology, 2015 - Elsevier
Cigarette smoking is currently the leading cause of preventable deaths and disability throughout
the world, being responsible for about five million premature deaths/year. Unfortunately, …

Biogenesis, trafficking and up-regulation of nicotinic ACh receptors

SF Colombo, F Mazzo, F Pistillo, C Gotti - Biochemical pharmacology, 2013 - Elsevier
Chronic nicotine exposure gives rise to neural adaptations that change whole cell physiology
and behaviour mainly by interacting with neuronal nicotinic acetylcholine receptors (…

The chemokine CCL2 mediates the seizure-enhancing effects of systemic inflammation

C Cerri, S Genovesi, M Allegra, F Pistillo… - Journal of …, 2016 - Soc Neuroscience
F, Number of isolated spikes per 10 min of recordings. No difference was found between
LPS and saline-injected epileptic mice (two-way repeated-measures ANOVA followed by Holm–…

The novel α7β2-nicotinic acetylcholine receptor subtype is expressed in mouse and human basal forebrain: biochemical and pharmacological characterization

M Moretti, M Zoli, AA George, RJ Lukas, F Pistillo… - Molecular …, 2014 - ASPET
We examined α 7 β 2 -nicotinic acetylcholine receptor (α 7 β 2 -nAChR) expression in mammalian
brain and compared pharmacological profiles of homomeric α 7 -nAChRs and α 7 β 2 -…

Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor

F Mazzo, F Pistillo, G Grazioso, F Clementi… - Journal of …, 2013 - Soc Neuroscience
F, Comparison of β4/α3 stoichiometry in wild-type and α3*-containing receptors. Lysates …
9F). Thus, as in the case of nicotine-treatment, a change in subunit stoichiometry of the …

Incidence of disease flare after BNT162b2 coronavirus disease 2019 vaccination in patients with rheumatoid arthritis in remission

R Bixio, D Bertelle, M Masia, F Pistillo… - ACR open …, 2021 - search.proquest.com
Table 1 Clinical characteristics of patients with rheumatoid arthritis undergoing vaccination
with BNT162b2 COVID-19 vaccine Characteristics Results Age, years±SD 62.2±13.2 Female …

In vivo chronic nicotine exposure differentially and reversibly affects upregulation and stoichiometry of α4β2 nicotinic receptors in cortex and thalamus

F Fasoli, M Moretti, M Zoli, F Pistillo, A Crespi… - …, 2016 - Elsevier
Studies with heterologous expression systems have shown that the α4β2 nicotinic acetylcholine
receptor (nAChR) subtype can exist in two stoichiometries (with two [(α4) 2 (β2) 3 ] or …

Bone Loss in Inflammatory Rheumatic Musculoskeletal Disease Patients Treated With Low‐Dose Glucocorticoids and Prevention by Anti‐Osteoporosis Medications

…, A Fassio, M Rossini, C Benini, F Pistillo… - Arthritis & …, 2023 - Wiley Online Library
Objective The negative effects of glucocorticoids on bone depend on dose and treatment
duration. However, it is unclear whether a safe dose exists, especially for patients with …

A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic …

…, A Gaimarri, I Manfredi, F Pistillo, F Clementi… - Molecular …, 2010 - ASPET
Long-term nicotine exposure changes neuronal acetylcholine nicotinic receptor (nAChR)
subtype expression in the brains of smokers and experimental animals. The aim of this study …