User profiles for G. Michalopoulos
George MichalopoulosUniversity of Pittsburgh Verified email at upmc.edu Cited by 45231 |
Liver regeneration
GK Michalopoulos - The liver: biology and pathobiology, 2020 - Wiley Online Library
… and Michalopoulos, G. Purification and biological characterization of human
hepatopoietin A., a polypeptide growth factor for hepatocytes. Cancer Res, 1989;49(12):3314–20. …
hepatopoietin A., a polypeptide growth factor for hepatocytes. Cancer Res, 1989;49(12):3314–20. …
Liver regeneration
GK Michalopoulos - Journal of cellular physiology, 2007 - Wiley Online Library
… This was discussed in the context of liver regeneration in a recent review (Michalopoulos
and Khan, 2005c). Though there is high level of redundancy between receptors and ligands, …
and Khan, 2005c). Though there is high level of redundancy between receptors and ligands, …
Liver regeneration: molecular mechanisms of growth control
GK Michalopoulos - Artificial Liver Support: Concepts, Methods, Results, 1990 - Springer
… Fleig WE, Hoss G (1989) Partial purification of rat hepatic stimulator substance and
characterization of its action on hepatoma cells and normal hepatocytes. Hepatology 9:240-248 …
characterization of its action on hepatoma cells and normal hepatocytes. Hepatology 9:240-248 …
Primary culture of parenchymal liver cells on collagen membranes: morphological and biochemical observations
G Michalopoulos, HC Pitot - Experimental cell research, 1975 - Elsevier
Comparative morphological and biochemical studies of primary cultures of parenchymal
liver cells from adult rat liver cultured on collagen-coated plates and floating collagen …
liver cells from adult rat liver cultured on collagen-coated plates and floating collagen …
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.
…, G Gaudino, R Zarnegar, GK Michalopoulos… - Oncogene, 1991 - europepmc.org
The human proto-oncogene c-MET encodes a heterodimeric 190 kDa transmembrane
protein (p190c-met) with structural features of a tyrosine kinase receptor. The ligand for this …
protein (p190c-met) with structural features of a tyrosine kinase receptor. The ligand for this …
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor.
…, G Hartmann, R Zarnegar, GK Michalopoulos - The EMBO …, 1991 - embopress.org
Scatter Factor (SF) is a fibroblast‐secreted protein which promotes motility and matrix invasion
of epithelial cells. Hepatocyte Growth Factor (HGF) is a powerful mitogen for hepatocytes …
of epithelial cells. Hepatocyte Growth Factor (HGF) is a powerful mitogen for hepatocytes …
Liver regeneration: biological and pathological mechanisms and implications
GK Michalopoulos, B Bhushan - Nature reviews Gastroenterology & …, 2021 - nature.com
The liver is the only solid organ that uses regenerative mechanisms to ensure that the liver-to-bodyweight
ratio is always at 100% of what is required for body homeostasis. Other solid …
ratio is always at 100% of what is required for body homeostasis. Other solid …
[HTML][HTML] Liver regeneration after partial hepatectomy: critical analysis of mechanistic dilemmas
GK Michalopoulos - The American journal of pathology, 2010 - Elsevier
Liver regeneration after partial hepatectomy is one of the most studied models of cell, organ,
and tissue regeneration. The complexity of the signaling pathways initiating and terminating …
and tissue regeneration. The complexity of the signaling pathways initiating and terminating …
[PDF][PDF] Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy
…, R Dhir, S Finkelstein, G Michalopoulos… - Journal of clinical …, 2004 - academia.edu
… Finally, the predictor list contains several genes in G protein signaling … G protein beta subunit,
G protein coupled receptor 12, and Rab-escorted protein 1. This implies a role for G protein …
G protein coupled receptor 12, and Rab-escorted protein 1. This implies a role for G protein …
Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically …
…, T Riley, TA Howard, GK Michalopoulos - The Journal of cell …, 1996 - rupress.org
… Released nuclei were pelleted by centrifugation at 800 g for 5 min, washed, and extracted
in 50 pxl of hypertonic extraction buffer (30 mM Hepes, pH 7.9, 25% glycerol, 450 mM NaCI, …
in 50 pxl of hypertonic extraction buffer (30 mM Hepes, pH 7.9, 25% glycerol, 450 mM NaCI, …