For over a decade it has been generally assumed that all the pharmacological and biochemical
actions of dopamine within the central nervous system and periphery were mediated by …

G protein-coupled receptors comprise a family of genes that share significant sequence
similarity. We have screened a rat genomic library under low stringency hybridization conditions …

The distribution of mRNA coding for the D2 dopamine receptor was studied in the rat brain
by in situ hybridization. A cDNA probe corresponding to the putative third cytosolic loop and …

Recent molecular characterization of the human D4 gene has revealed the existence of
various polymorphic forms of this receptor. These variations are found in the putative third …

Serotonin (5-HT) is a major neurotransmitter that influences various behaviors, neuronal
plasticity, learning, and memory in molluscs. Although the physiology of 5-HT transmission in …

An intronless gene encoding a serotonin receptor (5HT1D beta) has been cloned and
functionally expressed in mammalian fibroblast cultures. Based on the deduced amino acid …

Based on pharmacological, biochemical, and molecular criteria, multiple somatostatin
receptor(SSTR) subtypes selective for somatostatin(SST)-1 4 and-28 have been postulated to …

Parasympathetic stimulation of the heart, which provides protection from arrhythmias and
sudden death, involves activation of the G protein–coupled inward rectifying K + channel GIRK1…

A monoclonal antibody (mAb L6) to a small-cell lung carcinoma surface antigen recognizes
a common epitope of vasopressin-neurophysin and oxytocin-neurophysin in hypothalamic …

The peptides that represent the major components with alpha-endorphin- and gamma-endorphin-like
immunoreactivity in the rat neurointermediate lobe were purified to homogeneity …