Formyl peptide receptors (FPRs) are a small group of seven-transmembrane domain, G
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes and …

Leukocytes accumulate at sites of inflammation and microbial infection in direct response to
locally produced chemotactic factors, which signal through specific G protein-coupled …

Defensins contribute to host defense by disrupting the cytoplasmic membrane of microorganisms.
This report shows that human β-defensins are also chemotactic for immature dendritic …

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …

Emerging data indicate that progesterone has multiple non-reproductive functions in the
central nervous system to regulate cognition, mood, inflammation, mitochondrial function, …

… Su peptide is a specific agonist for FPRL1 receptor (Wang, JM, unpublished observation).
Su peptide was 99% pure as verified by mass spectrometry. LL-37 was synthesized by solid …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

Dear Editor, Today, the need for time-effective and cost-effective nucleic acid detection
methods is still growing in fields such as human genotyping and pathogen detection. Using …

We introduce Gaussian process dynamical models (GPDMs) for nonlinear time series
analysis, with applications to learning models of human pose and motion from high-dimensional …

Stroke is one of the most common causes of mortality and morbidity in the Western world. It
results from the occlusion of a cerebral artery followed by severe disturbances in blood …