Amyotrophic lateral sclerosis (ALS) is a neurodegenerative and fatal human disorder
characterized by progressive loss of motor neurons. Transgenic mouse models of ALS are very …

Amyotrophic lateral sclerosis is a lethal, adult‐onset disease characterized by progressive
degeneration of motoneurons. Recent data have suggested that the disease could be linked …

The level of expression of ion channels has been demonstrated to vary over a threefold to
fourfold range from neuron to neuron, although the expression of distinct channels may be …

Quantitative analysis of the dendritic arborizations of wild‐type (WT) and superoxide dismutase
1 (SOD1) postnatal mouse motoneurons was performed following intracellular staining …

There have been considerable interests in attempting to reverse the deficit because of an
SCI (spinal cord injury) by restoring neural pathways through the lesion and by rebuilding the …

A critical step in improving our understanding of the development of amyotrophic lateral
sclerosis (ALS) is to identify the factors contributing to the alterations in the excitability of …

Most neurodegenerative diseases become manifest at an adult age but abnormalities or
pathological symptoms appear earlier. It is important to identify the initial mechanisms …

… This work was funded by Inserm (Avenir grant to J-MG, post-doctoral fellowship to JA), the
Fyssen Foundation (J-MG), Conseil Général des Bouches du Rhône CG13 (J-MG) and the …

We studied the rapid changes in electrical properties of lumbar motoneurons between
postnatal days 3 and 9 just before mice weight-bear and walk. The input conductance and …

Antidromically identified lumbar motoneurons intracellularly recorded in the entire brainstem/spinal
cord preparation isolated from SOD1 (G85R) postnatal mice (P3-P10) were labelled …