Synaptic plasticity and translation initiation
E Klann, MD Antion, JL Banko, L Hou - Learning & memory, 2004 - learnmem.cshlp.org
It is widely accepted that protein synthesis, including local protein synthesis at synapses, is
required for several forms of synaptic plasticity. Local protein synthesis enables synapses to …
required for several forms of synaptic plasticity. Local protein synthesis enables synapses to …
The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampus
JL Banko, F Poulin, L Hou, CT DeMaria… - Journal of …, 2005 - Soc Neuroscience
Long-lasting synaptic plasticity and memory requires mRNA translation, yet little is known
as to how this process is regulated. To explore the role that the translation repressor 4E-BP2 …
as to how this process is regulated. To explore the role that the translation repressor 4E-BP2 …
[HTML][HTML] mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning
JE Ayala, Y Chen, JL Banko, DJ Sheffler… - …, 2009 - nature.com
Highly selective positive allosteric modulators (PAMs) of metabotropic glutamate receptor
subtype 5 (mGluR5) have emerged as a potential approach to treat positive symptoms …
subtype 5 (mGluR5) have emerged as a potential approach to treat positive symptoms …
Regulation of eukaryotic initiation factor 4E by converging signaling pathways during metabotropic glutamate receptor-dependent long-term depression
JL Banko, L Hou, F Poulin, N Sonenberg… - Journal of …, 2006 - Soc Neuroscience
Long-term depression (LTD) is an activity-dependent decrease in synaptic efficacy that can
be induced in hippocampal area CA1 by pharmacological application of the selective group I …
be induced in hippocampal area CA1 by pharmacological application of the selective group I …
Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density
…, DTS Pak, LW Babus, M Peters, JL Banko… - Learning & …, 2011 - learnmem.cshlp.org
Apolipoprotein receptors belong to an evolutionarily conserved surface receptor family that
has intimate roles in the modulation of synaptic plasticity and is necessary for proper …
has intimate roles in the modulation of synaptic plasticity and is necessary for proper …
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
…, TE Golde, EJ Weeber, J Banko… - Journal of …, 2010 - Soc Neuroscience
Molecular chaperones regulate the aggregation of a number of proteins that pathologically
misfold and accumulate in neurodegenerative diseases. Identifying ways to manipulate these …
misfold and accumulate in neurodegenerative diseases. Identifying ways to manipulate these …
Pre-MCI and MCI: neuropsychological, clinical, and imaging features and progression rates
…, Y Wu, J Banko, H Potter, MT Greig, J Schinka… - The American Journal of …, 2011 - Elsevier
Objective To compare clinical, imaging, and neuropsychological characteristics and longitudinal
course of subjects with pre-mild cognitive impairment (pre-MCI), who exhibit features of …
course of subjects with pre-mild cognitive impairment (pre-MCI), who exhibit features of …
[HTML][HTML] Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome
…, MM Peters, RD Burdine, C Dickey, JL Banko… - PloS one, 2011 - journals.plos.org
Angelman syndrome (AS), a genetic disorder occurring in approximately one in every 15,000
births, is characterized by severe mental retardation, seizures, difficulty speaking and ataxia…
births, is characterized by severe mental retardation, seizures, difficulty speaking and ataxia…
Defining mild cognitive impairment: impact of varying decision criteria on neuropsychological diagnostic frequencies and correlates
…, A Raj, MR Schoenberg, JL Banko… - The American Journal of …, 2010 - Elsevier
Objective To examine the impact of varying decision criteria on neuropsychological diagnostic
frequencies and on their correlates. Design Descriptive and correlational study. Setting …
frequencies and on their correlates. Design Descriptive and correlational study. Setting …
Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation
…, EC Arnold, JL Banko… - Proceedings of the …, 2011 - National Acad Sciences
Considerable evidence indicates that the general blockade of protein synthesis prevents
both the initial consolidation and the postretrieval reconsolidation of long-term memories. …
both the initial consolidation and the postretrieval reconsolidation of long-term memories. …