[HTML][HTML] The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in …
KS Sink, PJ McLaughlin, JAT Wood, C Brown… - …, 2008 - nature.com
Drugs that interfere with cannabinoid CB1 transmission suppress various food-motivated
behaviors, and it has been suggested that such drugs could be useful as appetite suppressants…
behaviors, and it has been suggested that such drugs could be useful as appetite suppressants…
Nucleus accumbens adenosine A2A receptors regulate exertion of effort by acting on the ventral striatopallidal pathway
…, LT Worden, CM Stopper, RG Port, KS Sink… - Journal of …, 2008 - Soc Neuroscience
Goal-directed actions are sensitive to work-related response costs, and dopamine in nucleus
accumbens is thought to modulate the exertion of effort in motivated behavior. Dopamine-…
accumbens is thought to modulate the exertion of effort in motivated behavior. Dopamine-…
Effects of continuously enhanced corticotropin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxiety
KS Sink, DL Walker, SM Freeman, EI Flandreau… - Molecular …, 2013 - nature.com
The lateral division of the bed nucleus of the stria terminalis (BNST), which forms part of the
circuitry regulating fear and anxiety, contains a large number of neurons expressing …
circuitry regulating fear and anxiety, contains a large number of neurons expressing …
The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist haloperidol on effort-related decision making in a T-maze cost/benefit …
The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist
haloperidol on effort-related decision making in a T-maze cost/benefit procedure | SpringerLink …
haloperidol on effort-related decision making in a T-maze cost/benefit procedure | SpringerLink …
Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety …
KS Sink, DL Walker, Y Yang, M Davis - Journal of Neuroscience, 2011 - Soc Neuroscience
Calcitonin gene-related peptide (CGRP) evokes anxiety-like responses when infused into
the lateral ventricle of rats. Because the bed nucleus of the stria terminalis (BNST) lies …
the lateral ventricle of rats. Because the bed nucleus of the stria terminalis (BNST) lies …
Cannabinoid CB1 antagonists and dopamine antagonists produce different effects on a task involving response allocation and effort-related choice in food-seeking …
KS Sink, VK Vemuri, T Olszewska, A Makriyannis… - …, 2008 - Springer
… papers that assessed chow intake separately showed that the doses of AM251 and AM4113
used in the present study also suppressed chow intake (McLaughlin et al. 2003; Sink et al. …
used in the present study also suppressed chow intake (McLaughlin et al. 2003; Sink et al. …
Potential anxiogenic effects of cannabinoid CB1 receptor antagonists/inverse agonists in rats: comparisons between AM4113, AM251, and the benzodiazepine …
KS Sink, KN Segovia, J Sink, PA Randall… - European …, 2010 - Elsevier
Cannabinoid CB1 inverse agonists suppress food-motivated behaviors, but may also
induce psychiatric effects such as depression and anxiety. To evaluate behaviors potentially …
induce psychiatric effects such as depression and anxiety. To evaluate behaviors potentially …
The adenosine A2A antagonist MSX-3 reverses the effort-related effects of dopamine blockade: differential interaction with D1 and D2 family antagonists
LT Worden, M Shahriari, AM Farrar, KS Sink… - …, 2009 - Springer
… were selected based upon pilot studies and also upon a recent publication (Sink et al. 2008).
Based upon the dose/response curves in the Sink et al. (2008) paper, the present doses of …
Based upon the dose/response curves in the Sink et al. (2008) paper, the present doses of …
The CB1 inverse agonist AM251, but not the CB1 antagonist AM4113, enhances retention of contextual fear conditioning in rats
KS Sink, KN Segovia, LE Collins, EJ Markus… - Pharmacology …, 2010 - Elsevier
The effects of CB1 antagonist/inverse agonists on the acquisition and consolidation of
conditioned fear remain uncertain. Recent studies suggest that the CB1 antagonist/inverse …
conditioned fear remain uncertain. Recent studies suggest that the CB1 antagonist/inverse …
Anxiogenic effects of CGRP within the BNST may be mediated by CRF acting at BNST CRFR1 receptors
KS Sink, A Chung, KJ Ressler, M Davis… - Behavioural brain …, 2013 - Elsevier
Calcitonin gene-related peptide (CGRP) acting within the bed nucleus of the stria terminalis
(BNST) increases anxiety as well as neural activation in anxiety-related structures, and …
(BNST) increases anxiety as well as neural activation in anxiety-related structures, and …